Tools for the OCNDS Research Community
schwartzlab.uconn.eduOCNDS CK2 K198R Ion Channel Predictor
The OCNDS ion channel predictor is a tool to identify possible CK2 wild type and K198R variant phosphorylation sites of human ion channels localized to the axon.
Proteins can be filtered by name and results show the 15mer sequence surrounding the phosphorylation site, as well as a calculated probability that the site is phosphorylated by WT CK2 or K198R CK2. For a more detailed methodology, please review the accompanying paper.
Quantitative Proteomics Database
The OCNDS database contains results from our TMT-labeled, highly quantitative mass spectrometry experiment involving five human cell lines, four of which contain mutations to CK2, and one genetic control. The values shown in each variant column are fold changes relative to the wild type.
The database can be searched looking at the proteome or phosphoproteome, using gene name or protein accession, and can be sorted by column. Future work will incorporate filtering and tool tips. This database as well as the experiments documented in it are part of a paper in progress.
